Swiss-born Hugues Martin has worked for the world's most prestigious hotels, so when he purchases a small, run-down place in New York, everyone thinks he must be crazy! He alone sees it for the rough diamond it is, transforming it into a beautiful boutique hotel of impeccable elegance, run with the precision and attention to detail he learnt through his hotelier training in Europe.
The Hotel Vend�me soon becomes renowned for its unparalleled service, and is the ideal New York refuge for the rich and famous, as well as a perfect home for Hugues' beautiful wife and their young daughter. But when his wife tires of his obsession for the hotel, she walks out on him for a notorious rock star, leaving Hugues a single parent to four-year-old Heloise.
And so the kind hotel staff quickly embrace the little girl, becoming Heloise's family and she has a happy upbringing, adored by the fascinating milieu of high-profile guests. Hugues' commitment to his work has heavily influenced his daughter, so he is delighted when she decides she wants to follow in his footsteps - hotelier training in Switzerland.
But for a father and daughter who have always relied solely on each other, how is Hugues going to cope with his daughter so far away? Will Heloise ever be able to accept another woman in her father's life? And will Hugues have to choose between them?
As life marches quickly on, the close-knit unit at Hotel Vend�me are forced to form new bonds, face the often bitter sweetness of life, and work out the true meaning of love and family against the backdrop of a glamorous hotel.