Publication date: July 2003
Digital Book format: PDF (Adobe DRM)
Neuroprotection describes a range of therapeutic strategies for preventing the death of neurons in cases of ocular trauma or disease. Many of these disorders are difficult to treat and neuroprotection offers hope to many patients. This book is intended as a practical tool to aid researchers and investigators in the field of ocular neuroprotection. It provides a well-organized account of the methods used to conduct neuroprotection research, the problems that may be encountered and possible solutions. The first fifteen chapters of Ocular Neuroprotection review research methods at the laboratory level. This section includes information on cell culture and animal models, neuroprotective drugs, various outcome measures and their applicability to human disease. The last three chapters of the book provides a hands-on description of some of the practical obstacles in implementing clinical trials.
Many retinal and optic nerve disorders have no effective therapy, or are treated incompletely and with considerable side effects. Recent advances have suggested the significant benefits associated with neuroprotection-that is, when treatment strategies are directed to photoreceptors, retinal ganglion cells, or other neural targets. Enter Ocular Neuroprotection, the only handbook of research methods in neuroprotection of ocular disease covering both laboratory and clinical levels, to aid researchers studying the prevention of neuronal death from these and other hard-to-treat ophthalmic disorders.